Deep MALDI - º¸ÀÌÁö ¾Ê´ø peakµéÀ» º¸¿©µå¸³´Ï´Ù! (Àû¿ëºÐ¾ß: blood, cancer sample µî)
 
 

Deep MALDI MS is the best technique for protein profiling from biological samples
ÀϹÝÀûÀÎ MALDIº¸´Ù ´õ ¸¹Àº shot¼ö·Î ÀÎÇØ Noise peak¿¡ ¹¯Çô º¸ÀÌÁö ¾Ê´ø peakµéÀ» º¸¿©µå¸³´Ï´Ù!

Bruker MALDI TOF
+Deep Learning software = ¡°Deep MALDI¡±

Deep MALDI  ƯÀåÁ¡
•  ±âÁ¸ MALDI-TOF¿¡ ºñÇØ ÈξÀ ´õ °¨µµ ³ôÀº °á°ú¸¦ Á¦°ø
•  Ãß°¡ÀûÀÎ »ùÇà Àüó¸® ¹æ¹ýÀÌ ÇÊ¿ä ¾ø´Â °£´ÜÇÑ »ùÇà Àüó¸®
•  Raw spectrum ensembleÀ¸·Î ¾ÈÁÁÀº ½ºÆåÆ®·³À» Á¦°ÅÇÏ¿© high qualityÀÇ ½ºÆåÆ®·³ ȹµæ
•  °¨¼ÒµÈ noise¿Í Çâ»óµÈ °¨µµ´Â °³¼±µÈ spectrumÀ» ¾òÀ» ¼ö ÀÖÀ½

Deep MALDI with deep learning spectral processing

Deep MALDI with deep learning spectral processing

Deep MALDI application

Blood proteome - serum, plasma µîÀÇ Ç÷¾× »ùÇÃÀ» ÅëÇÑ ¿¬±¸

Tumor& Cancer
Immunotherapy

e.g.
- ¼­·Î ´Ù¸¥ Á¾¾ç À¯ÇüÀÇ ¿¹ÈÄ ºÐ·ù (À¯¹æ, ³­¼Ò, MDS)
- ¸é¿ª ¿ä¹ý¿¡ ¹ÝÀÀÀ» º¸À̴ ȯÀÚÀÇ ºÐ·ù

Deep maldi¸¦ ÀÌ¿ëÇÑ Myelodysplastic syndrome (MDS)
°ñ¼öÀÌÇü¼º ÁõÈıº
•  Serum based test
•  UltrafleXtreme TOF ¸¦ »ç¿ëÇÏ¿© Deep MALDI ¿Í Deep Learning ¹æ½ÄÀ¸·Î serum ºÐ¼®(100K shots per sample)
•  Deep MALDI·Î ¾òÀº serum spectrum °á°ú¸¦ ±â¹ÝÀ¸·Î MDS¿¡ ÁÁÀº ¿¹ÈÄ¿Í ¾È ÁÁÀº ¿¹Èĸ¦ º¸ÀÌ´Â 2±×·ìÀ¸·Î ³ª´®
•  serum spectra¸¦ ÅëÇØ ³ª´« ±×·ì º° »ýÁ¸·üÀÌ ¿¹ÈÄ¿Í ¸Â¾Æ Deep MALDI spectrum ºÐ¼®À» ÅëÇØ MDS ȯÀÚ¸¦ À§ÇÑ Ä¡·á °èȹ¿¡ Á¤º¸¸¦ Á¦°øÇØ ÁÙ ¼ö ÀÖ´Ù.

Deep maldi¸¦ ÀÌ¿ëÇÑ Myelodysplastic syndrome (MDS)

•  ´õºÒ¾î Bruker»çÀÇ ´Ù¾çÇÑ MALDI TOF/TOF (autoflex speed, ultrafleXtreme, rapifleX) µµ °ø±ÞÇÏ°í ÀÖ»ç¿À´Ï ¸¹Àº °ü½É ºÎŹµå¸³´Ï´Ù.

BRUKER